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Phytomedicine 113 , 154539 (2023)

KPV: As a fragment of alpha-MSH, an endogenous hormone, KPV inherits a theoretically favorable safety profile

Its guidance on compounded-drug risks warns that contamination or incorrect concentrations can cause serious injury or death

Rather, age-related premutational lesions may have occurred in these cells that are converted to the authentic mutation (most commonly a glycine to arginine substitution at codon 1,138) following fertilization, as a consequence of aberrant DNA repair in the zygote [5, 6]